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TROPICAL AND TRAVEL DISEASES

This is an overview page of some tropical and travel diseases known.  It is information only and you should contact a medical doctor to ensure you have the correct prevention and/or diagnoses of these diseases.  Although, everything below has been researched (and proven correct on numerous occasions) Tropixman.com or its affiliates assume no responsibility.  Be careful out there.  

Malaria is one of the most widely known disease due to it’s horrible reactions.
Prevention:  Use these simple but effective techniques; use DEET containing insect repellent, all day and night (Note: Use a lower concentration for pregnant women and children).  Also treat clothing with permethrin and sleep under a new/treated mosquito net.  

Fungal infections (Athlete’s Foot/Jock Itch) thrive in humid environments.  
Prevention: Ensure you keep yourself clean and dry as a prevention.
Possible treatment: Use Clotrimazole (Lotrimin) cream or solution, Miconazole (Micatin) cream, or Tolnaftate (Tinactin) cream, powder or solution.  Avoid using Hydrocortizone.  

Diarrhea
Prevention:  Antidiarreals help to control diarrhea and cramping but should be avoided for the first 24 hours while your body is ridding itself of the irritant or infection.  Drink lots of “safe” water and other fluids to replace those lost.  
Possible treatment: Use Bismuth Subsalicylate (good ol’ Pepto Bismol) tablets or liquid, Loperamide (Immodium) capsules or liquid or a Oral Rehydration Solution like Pedialyte or ReVital.
For bloody diarrhea, you need to see a doctor and most likely start antibiotic or antiparacitic medicine in addition to prevention of dehydration.  Antibiotic choices include Cipro 500 mg twice daily for 1-3 days; floxin 400 mg twice daily for 1-3 days; furazolidone(furoxone) 100mg 4 times daily for 1-3 days for bacterial infection and for 7-10 days for giardiasis; trimethoprim/sulfamethoxazole DS 1 tab twice daily for 3 days, combing with loperamide increases effectiveness; metronidazole (Flagyl) 500 mg three times daily for 5-7 days for giardiasis.

Leishmaniasis – Skin sores
Prevention:  Avoid sand fly bites (same measures as in malaria prevention).  Miltefosine (Impavido), is a new drug for visceral and cutaneous leishmaniasis. The cure rate of miltefosine in phase III clinical trials is 95%.
Possible treatment: For visceral leishmaniasis (kala azar) and severe cutaneous and mucocutaneous leishmaniasis, intravenous sodium stibogluconate (Pentostam) 20 mg/kg daily for 30-40 days is usually curative.  For mild cutaneous leishmaniasis, dapsone 100 mg twice daily for 6 weeks, or Ketoconazole 600 mg daily for 28 days has been shown good results.

Amebiasis – Gastrointestinal infection
Prevention: Good hand washing, boil/filter water, cook food well, avoid fly-contaminated foods.  Avoid sharing towels.  
Possible treatment: Metronidazole(flagyl) 750 mg three times a day for 5 - 10 days, followed by Iodoquinol 650 mg three times a day for 20 days.

Giardiasis – Gastrointestinal and/or anorexia, malaise or fatigue
Prevention: Good hand washing, boil/filter water, cook food well, avoid anal-oral contact.
Possible treatment:  Metronidazole (flagyl) 500 mg three time a days for 7 days; Quinacrine (Atabrine) 100 mg three times a days for 7 days (not available in the United States); Tinidazole (Fasigyn) (not available in the U.S.) 2 gm daily for 1-3 days; Furazolidone (Furoxone) (not available in the U.S.) 100 mg four times daily for 7 to 10 days.

Schistosomiasis  -
Prevention: Avoid contaminated water (fresh water), chlorinated water and sea water is safe. Heat bath water to above 50 degree C or 122 degree F for more than five minutes, or stand water more than 48 hours in a container.
Possible treatment:  For Schistosoma mansoni and S. hematobium, praziquantil (Biltricide) is curative in a single dose of 40 mg/kg. For S. japonicum and S. mekongi, praziquantel 60 mg/kg is given in three divided doses 6 hours apart. Dexamethasone is a useful adjunct in the treatment of acute neuroschitosomiasis.

Yellow Fever
Prevention:  Vaccine every 10 years, avoid mosquito bites. Supportive therapy only, no cure.

Hepatitis A
Prevention:  Good hygiene, disinfections of food and water, vaccine, or immunoglobulin. No cure against the virus of hepatitis, but symptoms often disappear after a few weeks to several months. Vaccination is available for hepatitis A and B (and thus can help prevent hepatitis D as well).
Only supportive therapy for dehydration from diarrhea and vomiting, no cure. Avoid alcohol and food heavy on the liver.

Hepatitis B
Prevention:  Good hygiene, disinfections of food and water, vaccine, condoms during intercourse, avoid unscreened blood transfusion. Only supportive therapy for dehydration from diarrhea and vomiting; interferon may be useful in chronic hepatitis B, but no cure for either acute or chronic hepatitis B.

Hepatitis C
Prevention:  Avoid intravenous drug use, nasal cocaine use, unprotected sex, unscreened blood products. Supportive therapy for dehydration from diarrhea and vomiting; there is no cure but interferon may be useful in chronic hepatitis C.

Hepatitis D and E
Prevention:  D: Same transmission as B, but usually occurs after contracting B
E: Similar to A. Epidemic often occurs during big floods.

Bacterial skin infections (open sores, cuts)
Prevention: Keep wounds dry and clean, wash wounds with clean saline for disinfections.  Antibiotics—topically or orally.

Chagas Disease
Prevention:  Avoid assassin (a.k.a. kissing, ruduviid) bugs which hide in the adobe hut structure (thatched roof and mud walls); avoid blood transfusion in Latin America. Acute illness can be shortened with nifurtimox, but the side effects can be severe. No treatment for chronic disease.
Other cure in the acute stage can be done with Benznidazol or Ragonil

Cholera—caused by Vibrio cholera
Prevention:  Disinfect food and water, avoid raw or undercooked food or seafood (especially ceviche); vaccines are not recommended by WHO.  Fluid re-hydration, antibiotics (Cipro 1 gm as single dose, Floxin 800 mg as single dose, doxycycline, tetracycline, or furazolidone)

Dengue fever
Prevention: Avoid mosquito bites.  There is no cure for dengue fever, but usually all symptoms disappear after a week. Supportive treatment with rest, fluid re-hydration, and pain medication.

Filariasis (one type of roundworm) –-lymphatic filariasis (bancroftian or malayan filariasis) and subcutaneous filariasis (onchocerciasis—a.k.a. river blindness) and loiasis
Prevention:  Avoid mosquitoes, flies (especially black flies in Latin America, and red flies in Africa), and biting midges; prophylaxis with diethylcarbamazine (DEC) either weekly or monthly to prevent loiasis or lymphatic filariasis. There is no prophylactic drug for onchocerciasis. Do not use DEC if have previously been exposed to filariasis until treated and cleared of parasites. Diethylcarbamazine (hetrazan) or high-dose ivermectin (200 micrograms/kg) for lmphatic filariasis; ivermectin (150 micrograms/kg every 6 months for 1 year, then annually for 5 years) for onchoceriasis; diethylcarbamazine (75mg/kg total, but start with ¼ tablet per day and slowly work up to 3 tablets 3 times a day over a 3-week period to avoid anaphylactic reaction from destruction of the worms.) or ivermectin (400 microgram/kg) as a single dose for loiasis.

Typhoid Fever—caused by Salmonella typhi
Prevention:  Disinfect food and water, good hygiene, avoid contact with infected individuals, vaccines (oral or the new one-dose injectable) Antibiotics (Cipro, Floxin, ampicillin, trimethoprin/sulfamethoxazole, ceftriaxone, and chloramhenicol)—start self-treatment with antibiotic and see medical consultation if infection suspected.

Tropical ulcer
Prevention:  Avoid having open wounds, cleanse wound with saline if present, keep wound dry and clean. Antibiotic powder (not ointment) to keep wound clean and dry.

Rabies
Prevention:  Avoid rabid animals, vaccine.  Antibiotics—see medical consultation for specific type.
Worms Depend on types of worms, some worms can enter the skin by penetration, by oral ingestion such as roundworms in raw seafood, or by oral-anal route. Some worms require surgical removal, some can respond to Albendazole, mebendazole, etc., but there are many types of worms and need to seek medical consultation for the correct antiparasitic medication.

Leptospirosis—caused by bacteria in the urine of domestic livestock, dogs, and small rodents
Prevention:  Disinfect food and water, good hygiene.  Antibiotic (penicilline, doxycycline).

Hanta virus
Prevention:  Avoid drinking rodent infested water and being in a rodent infested area, breathing in aerosolized virus.  Supportive therapy only, no cure.

Cutaneous Larva Migrans (caused by various roundworms - nematodes
Prevention:  Transmitted through dog or cat feces. Skin exposure (most common through the feet).  Thiabendazole orally 25 to 50 mg/kg/day in two divided doses for 2 days. Second course given after 2 to 7 days if lesion continues to extend. (also high doze of 22mg/kg twice a day for 5 days is possible).
Strong side effects (anorexia, nausea, dizziness) lead to research of topical thiabendazole.

Myasis (infestation by larvae of flies)
Prevention:  The botfly fixes its eggs on insects bites. All insect bites could potentially lead to larvae infection.  Fill up the lesion with petroleum or with adhesive to suffocate larvae, then remove when dead. Treat infection or enlarge orifice with small incision and extract larvae.

CutaneTungiasis
Prevention:  The sand flea enters the skin where it resides in the epidermis and grows to the size of a small pea. The posterior of the flea remains in contact with the air. Pus-filled, itchy papules form around the protruding posterior of the flea, often leading to secondary infections.
Cut the lesion and remove the flea with tweezers.


Dehydration
Oral Rehydration Therapy:
Add 1 tsp of salt and 2-3 tsp of sugar or honey to 1 liter of water.
Mix 8 oz. of fruit juice with 3 cups (24 oz.) of water, and add 1 tsp of salt.
Mix together: 1 liter clean water, ½ tsp table salt, ¼ tsp salt substitute (provide potassium chloride), ½ tsp baking soda (provide bicarbonate), and 2-3 tbsp of table sugar, or 2 tbsp of honey or Karo syrup. If cannot obtain baking soda or salt substitute, use 1 tsp of table salt per liter of solution.

Steps of dehydration treatment technique:
vigorously drink 3-6 liters or more of full-strength oral re-hydration solution over 2-4 hours. Don’t stop as soon as thirst is quenched—drink enough to restore urine output.
After re-hydration, start eating if not vomiting, and continue to drink fluids to maintain hydration. The best fluids are dilute fruit juices and water. If not able to eat, use half-strength oral re-hydration solution (ORS) as a maintenance fluid.
If watery diarrhea continues after re-hydration, prevent recurrent dehydration by drinking 8-12 oz. of full-strength ORS after each watery stool. Continue to eat and also consume water as thirst dictates.
Start antibiotic for traveler’s diarrhea as soon as possible.
Use easy-to-digest starches as starting foods—salted crackers, lightly salted oatmeal, rice cereal, lightly salted rice or noodle soups, etc. BRAT diet (banana, rice, apple sauce, and toast) is also good. Advance diet as allowed to cooked meats and vegetables, and then normal diet.
Avoid dairy products, highly sugared fluids (including Gatorade), caffeine, alcoholic drinks, and high-fat foods.


Other Exposure Related Problems

Food Poisoning - Toxins & Chemicals

Ciguatera, … . Inquire with locals about fish most susceptible to toxins.

Mercury, PCBs, DDT and other chemicals.

Follow guidelines published in "public health advisories on fish consumption".

Poisonous plants (coming soon in Tropical Dangers section)

Che Chem (or poison wood)




Medical Kit

Cipro 500 mg - General Antibiotic (for diarrhea, wounds, tooth infection, etc.). Twice daily for 1-3 days

Floxin Antibiotic (for Giardiasis Amebiasis). See table above for dosage

Powdered Antibiotic (for tropical ulcers)

Polysporin ointment (topical Antibiotic)

Clotrimazole (anti-fungal cream, for rash)

Baby powder or Talc powder (to prevent fungal infections and rash)

Steri strip (to close wounds)

Ibuprofen (Motrin, Advil) Pain killer. 800mg (1 tab. 3 times a day with food)

Benadryl (for allergies, itching and rash). 25-50mg every 6 hours as needed

Hydrocortisone cream (1%). for rash that does not respond to anti-fungal cream. (Careful, if it's a fungus, it will increase!)

Lidocaine with epinephrine for anesthesia. Inject sub-cutaneously (Do not use on extremities - blocks blood circulation)

Oral prednisone (oral steroid) for inflammation. e.g. jellyfish sting, fire coral, etc. 40-60mg at a time once a day for 5 days.

Artenam, Mefloquine, Nivaquine (Malaria medicine to take as a cure only. See note)


Treating Water

Boiling; filtering (additional iodine treatment might be necessary for viruses); iodine tablets; Chlorine liquid.

Iodine Tablets (Port Aqua or Globuline) or Iodine crystal (Polar Pure).

Tincture of iodine 2%. Wait 2 hours after treating with 5 drops per quart.

Using Liquid Chlorine (laundry bleach)

Laundry bleach may be used if no other active ingredients (only sodium hypochlorite) are used. Find percentage of chlorine (usually 4-6%).
For 1% of Chlorine use 10 drops per liter of clear water.
For 4-6% use 2 drops per liter.
For 7 to 10% use 1 drop per liter.
If percentage unknown, use 10 drops per liter.
When murky water or very cold temperature, double the dosage of chlorine.
The chlorine taste can be removed with some lime, lemon, tea, licorice, or powdered drinks (gatorade, tang, etc.).